Across TCGA patient cohorts, ERVMER34-1 mutation is significantly associated with the RNA expression of many other genes, with 1,020 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERVMER34-1-associated genes across cancer lineages are H2AB2, RBMY1F, and SEPTIN14P5. Each is linked with ERVMER34-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERVMER34-1-to-partner and partner-to-ERVMER34-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVMER34-1→partner) and Y-score (partner→ERVMER34-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	H2AB2 →	+0.134	+9.057	<.001	.003	3	1
BRCA	RBMY1F →	+0.024	+9.057	<.001	.003	3	1
BRCA	SEPTIN14P5 →	+0.129	+8.055	<.001	.007	3	1
UCEC	IGLV2-8 →	+1.727	+2.584	<.001	.001	3	1
UCEC	IGHV3-41 →	+0.633	+2.606	.008	<.001	3	1
UCEC	DHRS11 →	+0.605	+3.617	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,020 associations by consensus.

Exploration

ERVMER34-1 survival (RNA) · tumor vs normal (RNA) · all ERVMER34-1 data types