ERVMER34-1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ERVMER34-1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ERVMER34-1-associated genes across cancer lineages are C2CD4B, MFRP, and OR9I1. Each is linked with ERVMER34-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERVMER34-1-to-partner and partner-to-ERVMER34-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVMER34-1→partner) and Y-score (partner→ERVMER34-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINC2CD4B →+0.032+3.684.002.00631
SKINMFRP →+0.014+3.684<.001.00631
LUNG_NSCLC_LUADOR9I1 →+0.026+6.266<.001<.00131
LUNG_NSCLC_LUADOR5T2 →+0.013+5.662<.001.00231
LUNG_NSCLC_LUADDUSP29 →+0.031+5.228<.001.00531
LARGE_INTESTINEC9orf153 →+0.164+3.497<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration