ERVK9-11

Across TCGA pan-cancer cohorts, ERVK9-11 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ERVK9-11 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ERVK9-11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ERVK9-11 expression acts as an unfavorable survival marker, although some lineages such as UVM and KIRC show a favorable association.

MESO, UVM, and KIRC are the cancer types where ERVK9-11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	II,III,IV	0.297	0.491	.002	98	view →
UVM	OS	Tertile	All	0.922	0.640	.001	70	view →
KIRC	OS	Quartile	All	0.868	0.713	<.001	59	view →
LGG	OS	Median	All	0.368	0.521	<.001	53	view →
UCS	DFS	Median	III,IV	0.623	0.220	<.001	42	view →
CESC	DFS	Tertile	III,IV	0.228	0.615	.013	38	view →
UCEC	OS	Quartile	All	0.867	0.950	.001	30	view →
SKCM	OS	Tertile	IV	0.781	0.250	<.001	23	view →
OV	OS	Quartile	III,IV	0.757	0.889	.014	22	view →
PAAD	DFS	Quartile	All	0.642	0.275	.008	11	view →
BLCA	DFS	Quartile	All	0.227	0.562	.013	10	view →
THCA	DFS	Median	All	0.892	0.768	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ERVK9-11–MESO (OS)

Open the MESO breakdown →