ERVK3-1

Across TCGA patient cohorts, ERVK3-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,204 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERVK3-1-associated proteins across cancer lineages are TRIM28, PNKP, and UBA2. Each is linked with ERVK3-1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ERVK3-1-to-partner and partner-to-ERVK3-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERVK3-1 versus TRIM28 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVK3-1→partner) and Y-score (partner→ERVK3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.494	+0.550	<.001	<.001	3	8
GBM	PNKP →	+0.375	+0.531	<.001	<.001	3	7
GBM	UBA2 →	+0.380	+0.414	<.001	<.001	3	6
GBM	SAE1 →	+0.447	+0.417	<.001	<.001	3	5
LSCC	ZNF460 →	+0.424	+0.324	<.001	<.001	3	5
OV	PPP5C →	+0.338	+0.612	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,204 associations by consensus.

ERVK3-1 vs TRIM28 — GBM

Explore this scatter interactively →