ERVK3-1

Across TCGA patient cohorts, ERVK3-1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,950 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ERVK3-1-associated genes across cancer lineages are TOMM40, CCDC9, and ZNF773. Each is linked with ERVK3-1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ERVK3-1-to-partner and partner-to-ERVK3-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERVK3-1 versus TOMM40 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVK3-1→partner) and Y-score (partner→ERVK3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TOMM40 →	+0.710	+0.332	.001	.002	3	4
OV	CCDC9 →	+0.732	+0.515	<.001	<.001	3	4
OV	ZNF773 →	+0.643	+0.513	.005	.002	3	4
OV	ZNF417 →	+0.786	+0.504	.004	.002	3	4
GBM	ZNF530 →	+0.464	+0.257	<.001	.002	3	4
OV	ZNF841 →	+1.062	+0.490	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,950 associations by consensus.

ERVK3-1 vs TOMM40 — HNSC

Explore this scatter interactively →