ERVK-28

Across TCGA patient cohorts, ERVK-28 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,623 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ERVK-28-associated GO terms across cancer lineages are mRNA 3'-end processing, DNA strand elongation, and Ribosomal large subunit biogenesis. Each is linked with ERVK-28 in more than 12 cancer types. Because this analysis shows association rather than direction, both ERVK-28-to-partner and partner-to-ERVK-28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-end processing grouped by ERVK-28-low versus ERVK-28-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVK-28→partner) and Y-score (partner→ERVK-28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	mRNA 3'-end processing →	+0.079	+0.169	<.001	<.001	3	12
STAD	DNA strand elongation →	+0.058	+0.111	<.001	<.001	3	12
STAD	Ribosomal large subunit biogenesis →	+0.065	+0.142	<.001	<.001	3	12
STAD	Nucleus organization →	+0.054	+0.107	<.001	<.001	3	12
ESCA	Nuclear envelope organization →	+0.061	+0.244	<.001	.005	2	13
STAD	RNA 3'-end processing →	+0.077	+0.166	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,623 associations by consensus.

mRNA 3'-end processing by ERVK-28 expression — STAD

Explore this box plot interactively →