ERVH-1

Across TCGA patient cohorts, ERVH-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,879 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ERVH-1-associated GO terms across cancer lineages are Inner mitochondrial membrane organization, Nucleoside phosphate biosynthetic process, and Cellular respiration. Each is linked with ERVH-1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ERVH-1-to-partner and partner-to-ERVH-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Inner mitochondrial membrane organization grouped by ERVH-1-low versus ERVH-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVH-1→partner) and Y-score (partner→ERVH-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Inner mitochondrial membrane organization →	+0.055	+0.161	<.001	<.001	3	12
DLBC	Nucleoside phosphate biosynthetic process →	+0.064	+0.096	<.001	.004	3	12
STAD	Cellular respiration →	+0.058	+0.151	<.001	<.001	3	12
STAD	Mitochondrial translation →	+0.062	+0.201	<.001	<.001	3	11
STAD	Mitochondrial respiratory chain complex assembly →	+0.059	+0.184	<.001	<.001	3	11
STAD	Nucleoside bisphosphate metabolic process →	+0.038	+0.128	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,879 associations by consensus.

Inner mitochondrial membrane organization by ERVH-1 expression — STAD

Explore this box plot interactively →