ERVFRD-1

Across TCGA patient cohorts, ERVFRD-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,642 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERVFRD-1-associated proteins across cancer lineages are BUB3, HNRNPH1, and WRNIP1. Each is linked with ERVFRD-1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERVFRD-1-to-partner and partner-to-ERVFRD-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERVFRD-1 versus BUB3 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVFRD-1→partner) and Y-score (partner→ERVFRD-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BUB3 →	+0.355	+0.422	<.001	<.001	3	5
GBM	HNRNPH1 →	+0.309	+0.452	<.001	<.001	3	5
GBM	WRNIP1 →	+0.436	+0.406	<.001	<.001	3	5
OV	TAGLN2_S163 →	-1.057	-0.090	<.001	.004	3	5
GBM	SUPT6H →	+0.290	+0.349	<.001	.002	3	5
GBM	HNRNPH3 →	+0.348	+0.470	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,642 associations by consensus.

ERVFRD-1 vs BUB3 — GBM

Explore this scatter interactively →