ERVE-1

Across TCGA patient cohorts, ERVE-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,116 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ERVE-1-associated proteins across cancer lineages are TOM1L1, HOOK2, and BSPRY. Each is linked with ERVE-1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERVE-1-to-partner and partner-to-ERVE-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERVE-1 versus TOM1L1 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVE-1→partner) and Y-score (partner→ERVE-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TOM1L1 →	+0.721	+1.563	<.001	<.001	3	6
OV	HOOK2 →	+0.402	+0.523	.003	.001	3	5
LUAD	BSPRY →	+0.455	+0.617	<.001	<.001	3	5
LSCC	EPB41L4B →	+0.547	+0.448	<.001	<.001	3	5
OV	PPP1R18_S368 →	-0.649	-0.488	.009	.002	3	4
OV	FERMT3 →	-0.599	-0.448	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,116 associations by consensus.

ERVE-1 vs TOM1L1 — BRCA

Explore this scatter interactively →