ERV3-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ERV3-1 mutation is significantly associated with the RNA expression of many other genes, with 3,219 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERV3-1-associated genes across cancer lineages are RNU1-17P, MIR620, and YBX1P9. Each is linked with ERV3-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERV3-1-to-partner and partner-to-ERV3-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERV3-1→partner) and Y-score (partner→ERV3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU1-17P →+0.220+2.495<.001<.00132
HNSCMIR620 →+0.355+5.608<.001.00232
CESCYBX1P9 →+0.037+3.595<.001.00532
CESCRNA5SP364 →+0.417+3.148.005.00632
UCECRNA5SP411 →+1.043+1.946<.001<.00132
UCECRNA5SP412 →+0.499+2.049<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,219 associations by consensus.

Exploration