Across TCGA cell cohorts, ERV3-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,527 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERV3-1-associated GO terms across cancer lineages are Protein localization to cytoplasmic stress granule, mRNA splice site recognition, and Regulation of nucleotide-excision repair. Each is linked with ERV3-1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ERV3-1-to-partner and partner-to-ERV3-1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERV3-1→partner) and Y-score (partner→ERV3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein localization to cytoplasmic stress granule →	+0.147	+1.694	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.115	+1.324	<.001	<.001	3	13
OVARY	Regulation of nucleotide-excision repair →	+0.097	+0.883	<.001	.007	3	12
OVARY	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.095	+0.940	<.001	.003	3	12
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.115	-1.503	<.001	<.001	3	12
PANCREAS	Protein polyubiquitination →	+0.058	+1.941	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,527 associations by consensus.

Exploration

ERV3-1 survival (RNA) · tumor vs normal (RNA) · all ERV3-1 data types