ERP44

Across TCGA pan-cancer cohorts, ERP44 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ERP44 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ERP44 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ERP44 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, LSCC, and GBM are the cancer types where ERP44 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.647	1.000	.005	15	view →
LSCC	OS	Median	II,III,IV	0.677	0.883	.013	14	view →
GBM	DFS	Quartile	All	0.658	0.828	.015	8	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
HNSC	DFS	Quartile	III,IV	0.919	0.638	.019	4	view →
LUAD	OS	Quartile	II,III,IV	0.302	0.910	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ERP44–CCRCC (OS)

Open the CCRCC breakdown →