ERP44

Across TCGA patient cohorts, ERP44 protein abundance is significantly associated with the RNA expression of many other genes, with 14,822 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERP44-associated genes across cancer lineages are FUZ, SEC61B, and RPL22. Each is linked with ERP44 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERP44-to-partner and partner-to-ERP44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERP44 versus FUZ in CCRCC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERP44→partner) and Y-score (partner→ERP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FUZ →	-0.581	-0.274	<.001	<.001	3	5
BRCA	SEC61B →	+0.342	+0.254	<.001	<.001	3	5
HNSC	RPL22 →	-0.510	-0.170	<.001	.001	3	5
HNSC	WDR35 →	-0.479	-0.204	.001	<.001	3	5
BRCA	UBIAD1 →	-0.464	-0.314	<.001	<.001	3	5
BRCA	SGSM2 →	-0.651	-0.375	.005	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,822 associations by consensus.

ERP44 vs FUZ — CCRCC

Explore this scatter interactively →