ERMN

Across TCGA patient cohorts, ERMN RNA expression is significantly associated with the protein abundance of many other proteins, with 25,588 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERMN-associated proteins across cancer lineages are PLXNC1, PPP1R18, and TBC1D1. Each is linked with ERMN in more than 6 cancer types. Because this analysis shows association rather than direction, both ERMN-to-partner and partner-to-ERMN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERMN versus PLXNC1 in CCRCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMN→partner) and Y-score (partner→ERMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLXNC1 →	+0.446	+0.538	<.001	<.001	3	7
OV	PPP1R18 →	+0.601	+0.864	<.001	.005	3	7
OV	TBC1D1 →	+0.464	+0.854	<.001	<.001	3	7
OV	NUP35 →	-0.318	-0.712	<.001	.007	3	7
LSCC	ELMO2 →	+0.292	+0.472	<.001	<.001	3	7
COAD	MRPS9 →	-0.289	-0.642	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,588 associations by consensus.

ERMN vs PLXNC1 — CCRCC

Explore this scatter interactively →