ERMN

Across TCGA patient cohorts, ERMN protein abundance is significantly associated with the RNA expression of many other genes, with 8,536 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERMN-associated genes across cancer lineages are DOK5, SLC9A3R1, and MAPK8IP1. Each is linked with ERMN in more than 1 cancer types. Because this analysis shows association rather than direction, both ERMN-to-partner and partner-to-ERMN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERMN versus DOK5 in UCEC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMN→partner) and Y-score (partner→ERMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DOK5 →	-0.712	-0.638	.002	.003	3	2
UCEC	SLC9A3R1 →	+0.701	+0.535	.001	.004	3	2
UCEC	MAPK8IP1 →	+0.958	+1.098	<.001	<.001	3	2
LSCC	SHFL →	-0.907	-1.314	.001	.004	3	2
UCEC	CYP2J2 →	+0.957	+0.759	<.001	<.001	3	2
UCEC	ADAMTS8 →	+1.491	+0.712	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,536 associations by consensus.

ERMN vs DOK5 — UCEC

Explore this scatter interactively →