ERMN

Across TCGA cell cohorts, ERMN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,512 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ERMN-associated GO terms across cancer lineages are Protein N-linked glycosylation, Nucleobase-containing compound transport, and Protein destabilization. Each is linked with ERMN in more than 5 cancer types. Because this analysis shows association rather than direction, both ERMN-to-partner and partner-to-ERMN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein N-linked glycosylation grouped by ERMN-low versus ERMN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMN→partner) and Y-score (partner→ERMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein N-linked glycosylation →	+0.088	+0.347	<.001	.004	2	6
BLOOD_Myeloma	Nucleobase-containing compound transport →	+0.053	+1.021	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.108	+0.083	<.001	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Protein exit from endoplasmic reticulum →	+0.088	+0.069	.004	.007	3	5
UPPER_AERODIGESTIVE_TRACT	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.115	+0.088	<.001	<.001	2	6
CNS	Regulation of synaptic activity →	+0.759	+0.373	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,512 associations by consensus.

Protein N-linked glycosylation by ERMN expression — BONE

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