ERMARD

Across TCGA patient cohorts, ERMARD protein abundance is significantly associated with the RNA expression of many other genes, with 283 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERMARD-associated genes across cancer lineages are UPB1, PIK3IP1, and SLC5A1. Each is linked with ERMARD in more than 1 cancer types. Because this analysis shows association rather than direction, both ERMARD-to-partner and partner-to-ERMARD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERMARD versus UPB1 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMARD→partner) and Y-score (partner→ERMARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UPB1 →	-0.158	-0.411	.007	.002	3	1
LSCC	PIK3IP1 →	-0.632	-0.395	.001	.004	3	1
LSCC	SLC5A1 →	-1.472	-0.465	.005	.006	3	1
LSCC	TOM1 →	-0.361	-0.377	.005	.006	3	1
LSCC	SGSM3 →	-0.300	-0.512	.001	.006	3	1
LSCC	SIRPB1 →	-0.707	-0.605	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 283 associations by consensus.

ERMARD vs UPB1 — LSCC

Explore this scatter interactively →