ERMARD

Across TCGA patient cohorts, ERMARD mutation is significantly associated with the RNA expression of many other genes, with 3,146 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERMARD-associated genes across cancer lineages are RNA5SP420, OR7E117P, and MARK3P3. Each is linked with ERMARD in more than 2 cancer types. Because this analysis shows association rather than direction, both ERMARD-to-partner and partner-to-ERMARD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP420 grouped by ERMARD-low versus ERMARD-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMARD→partner) and Y-score (partner→ERMARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP420 →	+0.399	+4.309	.003	.007	3	3
SKCM	OR7E117P →	+0.022	+3.356	<.001	.005	3	2
SKCM	MARK3P3 →	+0.063	+2.414	.008	.006	3	2
LUAD	MIR4472-1 →	+0.459	+4.554	<.001	.009	3	2
LUAD	SPRING1P1 →	+0.103	+6.108	<.001	.001	3	2
CESC	TRAJ12 →	+0.852	+4.193	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,146 associations by consensus.

RNA5SP420 by ERMARD expression — LUSC

Explore this box plot interactively →