ERMARD

Across TCGA cell cohorts, ERMARD mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ERMARD-associated genes across cancer lineages are FCN2, GPR101, and PNLIP. Each is linked with ERMARD in more than 1 cancer types. Because this analysis shows association rather than direction, both ERMARD-to-partner and partner-to-ERMARD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCN2 grouped by ERMARD-low versus ERMARD-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMARD→partner) and Y-score (partner→ERMARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FCN2 →	+0.813	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	GPR101 →	+0.015	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	PNLIP →	+0.006	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR6M1 →	+0.034	+5.228	.002	.005	3	1
LARGE_INTESTINE	UTF1 →	+0.028	+5.217	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FCN2 by ERMARD expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →