ERLIN1

Across TCGA pan-cancer cohorts, ERLIN1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ERLIN1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ERLIN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ERLIN1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where ERLIN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.505	0.727	.013	17	view →
PDAC	DFS	Tertile	IV	0.959	0.409	.049	9	view →
CCRCC	OS	Median	II,III,IV	0.454	1.000	.014	6	view →
HNSC	OS	Quartile	IV	0.925	0.662	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ERLIN1–LUAD (DFS)

Open the LUAD breakdown →