ERLIN1

Across TCGA cell cohorts, ERLIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,691 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERLIN1-associated GO terms across cancer lineages are DNA synthesis involved in DNA repair, Spindle elongation, and Mitotic spindle midzone assembly. Each is linked with ERLIN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ERLIN1-to-partner and partner-to-ERLIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA synthesis involved in DNA repair grouped by ERLIN1-low versus ERLIN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERLIN1→partner) and Y-score (partner→ERLIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA synthesis involved in DNA repair →	+0.098	+1.359	<.001	<.001	3	13
KIDNEY	Spindle elongation →	+0.222	+0.920	<.001	<.001	3	13
KIDNEY	Mitotic spindle midzone assembly →	+0.178	+0.768	<.001	.002	3	13
KIDNEY	Mitotic spindle elongation →	+0.178	+0.768	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of nuclear cell cycle DNA replication →	+0.154	+1.019	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cytokinesis →	+0.166	+1.114	.002	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,691 associations by consensus.

DNA synthesis involved in DNA repair by ERLIN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →