ERICH1

Across TCGA patient cohorts, ERICH1 RNA expression is significantly associated with the mutation status of many other genes, with 8,981 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH1-associated genes across cancer lineages are PIK3CA, DNAH1, and AHNAK2. Each is linked with ERICH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERICH1-to-partner and partner-to-ERICH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIK3CA grouped by ERICH1-low versus ERICH1-high in LGG.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH1→partner) and Y-score (partner→ERICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	PIK3CA →	+2.392	+0.284	<.001	<.001	3	5
SKCM	DNAH1 →	+1.586	+0.224	.003	.003	3	4
COAD	AHNAK2 →	+2.110	+0.284	<.001	<.001	3	4
ESCA	LRP1B →	+1.793	+0.447	.004	<.001	3	3
SKCM	NOTCH2 →	+2.647	+0.359	.004	.002	3	3
SKCM	ADAMTS7 →	+1.543	+0.291	.008	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,981 associations by consensus.

PIK3CA by ERICH1 expression — LGG

Explore this box plot interactively →