ERICH1

Across TCGA pan-cancer cohorts, ERICH1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ERICH1 data layer compared with 5 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ERICH1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ERICH1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and READ show a favorable association.

SKCM, READ, and KICH are the cancer types where ERICH1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	III,IV	0.537	0.311	<.001	85	view →
READ	OS	Median	II,III,IV	0.858	0.474	<.001	59	view →
KICH	OS	Tertile	All	0.505	1.000	.002	45	view →
LGG	OS	Median	All	0.749	0.871	<.001	45	view →
MESO	DFS	Median	IV	0.180	0.476	.008	39	view →
ACC	DFS	Tertile	II,III,IV	0.544	0.941	.003	35	view →
HNSC	DFS	Quartile	IV	0.363	0.238	.007	31	view →
BLCA	DFS	Tertile	All	0.126	0.584	<.001	26	view →
LIHC	DFS	Tertile	All	0.358	0.608	.004	25	view →
KIRC	DFS	Quartile	All	0.788	0.503	.003	16	view →
COAD	DFS	Median	All	0.590	0.778	.002	14	view →
ESCA	OS	Median	All	0.449	1.000	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ERICH1–SKCM (OS)

Open the SKCM breakdown →