ERICH1

Across TCGA patient cohorts, ERICH1 mutation is significantly associated with the RNA expression of many other genes, with 895 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH1-associated genes across cancer lineages are GUCA1B, BRCA1, and TAF9. Each is linked with ERICH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ERICH1-to-partner and partner-to-ERICH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA1B grouped by ERICH1-low versus ERICH1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH1→partner) and Y-score (partner→ERICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GUCA1B →	+0.365	+2.606	.008	.005	3	3
UCEC	BRCA1 →	+0.591	+1.925	.001	.005	3	3
UCEC	TAF9 →	+0.409	+1.925	.005	.005	3	2
SKCM	RNU7-18P →	+0.528	+3.106	.007	.004	3	2
LUSC	MTND1P36 →	+0.064	+3.372	.009	<.001	3	2
UCEC	CCDC43 →	+0.479	+2.939	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 895 associations by consensus.

GUCA1B by ERICH1 expression — UCEC

Explore this box plot interactively →