ERICH1

Across TCGA cell cohorts, ERICH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,384 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ERICH1-associated GO terms across cancer lineages are Positive regulation of telomere capping, Pre-mRNA catabolic process, and Negative regulation of sister chromatid cohesion. Each is linked with ERICH1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ERICH1-to-partner and partner-to-ERICH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomere capping grouped by ERICH1-low versus ERICH1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH1→partner) and Y-score (partner→ERICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of telomere capping →	+0.118	+1.074	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Pre-mRNA catabolic process →	+0.146	+0.950	.001	<.001	3	13
SOFT_TISSUE	Negative regulation of sister chromatid cohesion →	+0.139	+0.926	<.001	<.001	3	13
LUNG_SCLC	Protein localization to chromosome, telomeric region →	+0.091	+1.002	.001	.002	3	13
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.088	+0.626	<.001	<.001	3	12
BLOOD_Myeloma	Microtubule anchoring →	+0.067	+0.844	.004	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,384 associations by consensus.

Positive regulation of telomere capping by ERICH1 expression — KIDNEY

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