ERICH1

Across TCGA cell cohorts, ERICH1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERICH1-associated genes across cancer lineages are MAGEB5, NPVF, and SPRR2B. Each is linked with ERICH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERICH1-to-partner and partner-to-ERICH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by ERICH1-low versus ERICH1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH1→partner) and Y-score (partner→ERICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MAGEB5 →	+0.041	+5.339	<.001	<.001	3	1
STOMACH	NPVF →	+0.020	+5.285	<.001	.003	3	1
STOMACH	SPRR2B →	+0.040	+5.285	<.001	.003	3	1
STOMACH	MS4A13 →	+0.133	+5.285	<.001	.003	3	1
SKIN	BTN1A1 →	+0.216	+4.095	<.001	.009	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

MAGEB5 by ERICH1 expression — OVARY

Explore this box plot interactively →