ERI3-IT1

Across TCGA pan-cancer cohorts, ERI3-IT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ERI3-IT1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ERI3-IT1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ERI3-IT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, KICH, and THCA are the cancer types where ERI3-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.780	0.621	<.001	102	view →
KICH	DFS	Quartile	II,III,IV	0.262	0.897	.004	56	view →
THCA	DFS	Median	All	0.779	0.899	.007	54	view →
ACC	OS	Quartile	II,III,IV	0.181	0.848	<.001	47	view →
LGG	DFS	Tertile	All	0.772	0.892	<.001	35	view →
DLBC	DFS	Tertile	III,IV	0.077	1.000	.017	29	view →
LIHC	OS	Quartile	II,III,IV	0.521	0.760	.001	29	view →
LUSC	DFS	Median	III,IV	0.571	0.732	.032	25	view →
READ	OS	Quartile	All	1.000	0.540	.005	21	view →
CESC	DFS	Tertile	All	0.763	0.850	.013	16	view →
LUAD	OS	Median	III,IV	0.769	0.553	.001	15	view →
THYM	OS	Median	II,III,IV	0.883	1.000	.009	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ERI3-IT1–HNSC (DFS)

Open the HNSC breakdown →