ERH

Across TCGA patient cohorts, ERH RNA expression is significantly associated with the protein abundance of many other proteins, with 13,785 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERH-associated proteins across cancer lineages are MTHFD1, SUPT16H, and YLPM1. Each is linked with ERH in more than 8 cancer types. Because this analysis shows association rather than direction, both ERH-to-partner and partner-to-ERH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERH versus MTHFD1 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERH→partner) and Y-score (partner→ERH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTHFD1 →	+0.402	+0.503	<.001	<.001	3	9
GBM	SUPT16H →	+0.441	+0.426	<.001	<.001	3	8
GBM	YLPM1 →	+0.324	+0.430	<.001	<.001	3	8
GBM	UBR7 →	+0.306	+0.341	<.001	<.001	3	7
COAD	NAA35 →	+0.231	+0.525	<.001	<.001	3	7
GBM	PPP4R3A →	+0.327	+0.399	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,785 associations by consensus.

ERH vs MTHFD1 — GBM

Explore this scatter interactively →