ERGIC1

Across TCGA patient cohorts, ERGIC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,693 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ERGIC1-associated proteins across cancer lineages are RNF14, RUFY1, and SEC23B. Each is linked with ERGIC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERGIC1-to-partner and partner-to-ERGIC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERGIC1 versus RNF14 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERGIC1→partner) and Y-score (partner→ERGIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RNF14 →	+0.374	+0.562	<.001	.003	3	6
OV	RUFY1 →	+0.530	+0.999	<.001	<.001	3	6
BRCA	SEC23B →	+0.305	+0.743	<.001	<.001	3	6
LUAD	ABCC3 →	+0.787	+0.590	<.001	<.001	3	6
BRCA	ARFGEF3_S2081 →	+1.174	+0.824	<.001	<.001	3	5
HNSC	NPM1 →	+0.359	+0.460	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,693 associations by consensus.

ERGIC1 vs RNF14 — OV

Explore this scatter interactively →