ERGIC1

Across TCGA cell cohorts, ERGIC1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ERGIC1-associated genes across cancer lineages are AVP, HNRNPCL4, and GSG1L2. Each is linked with ERGIC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERGIC1-to-partner and partner-to-ERGIC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ERGIC1-low versus ERGIC1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERGIC1→partner) and Y-score (partner→ERGIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.068	+4.217	<.001	.001	3	1
LARGE_INTESTINE	HNRNPCL4 →	+0.054	+3.793	.001	.007	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

AVP by ERGIC1 expression — LARGE_INTESTINE

Explore this box plot interactively →