ERFE

Across TCGA cell cohorts, ERFE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,766 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ERFE-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Nucleic acid transport, and RNA transport. Each is linked with ERFE in more than 7 cancer types. Because this analysis shows association rather than direction, both ERFE-to-partner and partner-to-ERFE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by ERFE-low versus ERFE-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERFE→partner) and Y-score (partner→ERFE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of telomerase RNA localization to Cajal body →	+0.091	+1.518	.001	<.001	3	8
BONE	Nucleic acid transport →	+0.133	+2.181	<.001	.001	3	8
BONE	RNA transport →	+0.133	+2.181	<.001	.001	3	8
BLOOD_Myeloma	Mitotic sister chromatid segregation →	+0.075	+0.724	.001	.009	3	8
BLOOD_Myeloma	Sister chromatid segregation →	+0.072	+0.724	.001	.009	3	8
LARGE_INTESTINE	Mitochondrion localization →	+0.055	+1.087	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,766 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by ERFE expression — OESOPHAGUS

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