EREG

Across TCGA patient cohorts, EREG RNA expression is significantly associated with the protein abundance of many other proteins, with 15,996 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EREG-associated proteins across cancer lineages are TNKS1BP1_S1073, STRN3_S229, and POGZ. Each is linked with EREG in more than 5 cancer types. Because this analysis shows association rather than direction, both EREG-to-partner and partner-to-EREG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EREG versus TNKS1BP1_S1073 in HNSC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EREG→partner) and Y-score (partner→EREG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TNKS1BP1_S1073 →	+0.513	+1.490	<.001	<.001	3	6
LSCC	STRN3_S229 →	+0.458	+1.266	<.001	<.001	3	6
HNSC	POGZ →	-0.243	-1.490	<.001	<.001	3	5
LSCC	PPP1R18_S224 →	+0.733	+1.271	<.001	<.001	3	5
LSCC	PXN →	+0.310	+0.996	<.001	<.001	3	5
GBM	NEO1 →	-0.364	-0.518	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,996 associations by consensus.

EREG vs TNKS1BP1_S1073 — HNSC

Explore this scatter interactively →