ERCC8-AS1

Across TCGA patient cohorts, ERCC8-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,531 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERCC8-AS1-associated proteins across cancer lineages are DDX42, SMARCD1, and TRIM28. Each is linked with ERCC8-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ERCC8-AS1-to-partner and partner-to-ERCC8-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERCC8-AS1 versus DDX42 in GBM, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC8-AS1→partner) and Y-score (partner→ERCC8-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDX42 →	+0.232	+0.502	.003	.006	3	4
GBM	SMARCD1 →	+0.426	+0.568	<.001	.002	3	3
GBM	TRIM28 →	+0.396	+0.478	.001	.009	3	3
LSCC	MYEF2 →	+0.490	+0.301	.002	.008	3	3
LSCC	NXF1 →	+0.239	+0.553	<.001	<.001	3	3
PDAC	PCBP2 →	+0.353	+0.456	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,531 associations by consensus.

ERCC8-AS1 vs DDX42 — GBM

Explore this scatter interactively →