Across TCGA patient cohorts, ERC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,933 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERC2-associated proteins across cancer lineages are MAP1B_S614, MAP1B_S1016, and UCHL1. Each is linked with ERC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERC2-to-partner and partner-to-ERC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERC2→partner) and Y-score (partner→ERC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1B_S614 →	+1.724	+0.876	<.001	<.001	3	6
LSCC	MAP1B_S1016 →	+1.153	+0.969	<.001	.001	3	5
HNSC	UCHL1 →	+1.266	+0.857	<.001	<.001	3	5
BRCA	PM20D2 →	+0.613	+0.194	.004	.008	3	4
BRCA	PSAT1 →	+0.739	+0.199	.008	.002	3	4
GBM	AFAP1L1 →	-0.391	-0.832	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,933 associations by consensus.

Exploration

ERC2 survival (RNA) · tumor vs normal (RNA) · all ERC2 data types