EQTN

Across TCGA patient cohorts, EQTN protein abundance is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EQTN-associated genes across cancer lineages are RAD50, OR1J1, and COQ8A. Each is linked with EQTN in more than 1 cancer types. Because this analysis shows association rather than direction, both EQTN-to-partner and partner-to-EQTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EQTN versus RAD50 in UCEC, with a Pearson correlation of -0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EQTN→partner) and Y-score (partner→EQTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD50 →	-0.825	-1.094	.005	.002	3	1
UCEC	OR1J1 →	-1.390	-1.094	.001	.002	3	1
UCEC	COQ8A →	-0.705	-1.094	<.001	.002	3	1
UCEC	TNFRSF10D →	-2.719	-1.094	.006	.002	3	1
UCEC	NUDT4 →	+0.544	+0.574	.005	.009	3	1
UCEC	NPIPP1 →	+1.174	+1.094	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

EQTN vs RAD50 — UCEC

Explore this scatter interactively →