EPX

Across TCGA cell cohorts, EPX mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EPX-associated genes across cancer lineages are GALP, CTIF, and CLEC4E. Each is linked with EPX in more than 1 cancer types. Because this analysis shows association rather than direction, both EPX-to-partner and partner-to-EPX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALP grouped by EPX-low versus EPX-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPX→partner) and Y-score (partner→EPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	GALP →	+0.033	+5.169	<.001	.004	3	1
BLOOD_Leukemia	CTIF →	+1.240	+3.199	.001	.007	3	1
BLOOD_Leukemia	CLEC4E →	+0.828	+3.008	<.001	.004	3	1
BLOOD_Leukemia	SPATA3 →	+0.015	+3.569	.001	.009	3	1
BLOOD_Leukemia	OR6C75 →	+0.005	+3.569	<.001	.009	3	1
BLOOD_Leukemia	CTXN3 →	+0.006	+2.979	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

GALP by EPX expression — BONE

Explore this box plot interactively →