EPS8L2

Across TCGA patient cohorts, EPS8L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,430 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPS8L2-associated proteins across cancer lineages are EPS8L2_S570, PKP3, and EPS8L2_S240. Each is linked with EPS8L2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPS8L2-to-partner and partner-to-EPS8L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPS8L2 versus EPS8L2_S570 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L2→partner) and Y-score (partner→EPS8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EPS8L2_S570 →	+1.108	+0.998	<.001	<.001	3	7
HNSC	PKP3 →	+0.697	+0.763	<.001	<.001	3	6
GBM	EPS8L2_S240 →	+1.256	+0.688	<.001	<.001	3	6
LUAD	TOM1L1 →	+0.554	+0.673	<.001	<.001	3	5
PDAC	PKP3_S331 →	+0.794	+0.452	<.001	<.001	3	5
LSCC	ESRP2 →	+0.478	+0.614	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,430 associations by consensus.

EPS8L2 vs EPS8L2_S570 — GBM

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