EPS8L2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EPS8L2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,934 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPS8L2-associated genes across cancer lineages are TMBIM1, RASSF7, and SPATS2. Each is linked with EPS8L2 in more than 7 cancer types. Because this analysis shows association rather than direction, both EPS8L2-to-partner and partner-to-EPS8L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPS8L2 versus TMBIM1 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L2→partner) and Y-score (partner→EPS8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTMBIM1 →+0.707+0.594<.001<.00128
HNSCRASSF7 →+1.122+0.568<.001<.00137
GBMSPATS2 →-0.553-0.827<.001<.00136
HNSCCD151 →+0.865+0.565<.001<.00127
BRCAPHLDA2 →+1.351+0.331<.001<.00136
HNSCPKP3 →+0.994+0.619<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,934 associations by consensus.

EPS8L2 vs TMBIM1 — HNSC

Per-sample scatter of EPS8L2 vs TMBIM1 in HNSC (Pearson r = 0.28).

Explore this scatter interactively →

Exploration