EPS8L2

Across TCGA patient cohorts, EPS8L2 mutation is significantly associated with the RNA expression of many other genes, with 661 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPS8L2-associated genes across cancer lineages are LINC01935, OR6D1P, and LRIT1. Each is linked with EPS8L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPS8L2-to-partner and partner-to-EPS8L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01935 grouped by EPS8L2-low versus EPS8L2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L2→partner) and Y-score (partner→EPS8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC01935 →	+0.095	+4.224	.002	.003	3	3
HNSC	OR6D1P →	+0.133	+3.780	<.001	.007	3	3
STAD	LRIT1 →	+0.228	+3.895	<.001	.004	3	2
HNSC	RNU2-50P →	+0.363	+3.813	<.001	.007	3	2
COAD	HEXIM1 →	+0.526	+3.210	.006	.009	3	2
COAD	MIR1288 →	+0.283	+3.212	.009	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 661 associations by consensus.

LINC01935 by EPS8L2 expression — HNSC

Explore this box plot interactively →