EPS8L2

Across TCGA cell cohorts, EPS8L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,644 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EPS8L2-associated GO terms across cancer lineages are Protein localization to plasma membrane, Negative regulation of actin filament polymerization, and Rho protein signal transduction. Each is linked with EPS8L2 in more than 14 cancer types. Because this analysis shows association rather than direction, both EPS8L2-to-partner and partner-to-EPS8L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to plasma membrane grouped by EPS8L2-low versus EPS8L2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L2→partner) and Y-score (partner→EPS8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to plasma membrane →	+0.085	+2.770	.001	.002	3	15
PANCREAS	Negative regulation of actin filament polymerization →	+0.202	+1.270	<.001	<.001	3	14
OESOPHAGUS	Rho protein signal transduction →	+0.213	+3.127	<.001	<.001	3	14
BREAST	Assembly of actomyosin apparatus involved in cytokinesis →	+0.187	+1.880	<.001	.003	3	14
BREAST	Actomyosin contractile ring assembly →	+0.187	+1.880	<.001	.003	3	14
KIDNEY	Response to ketone →	+0.092	+1.271	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,644 associations by consensus.

Protein localization to plasma membrane by EPS8L2 expression — OESOPHAGUS

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