EPS8L1

Across TCGA cell cohorts, EPS8L1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EPS8L1-associated genes across cancer lineages are C10orf53, OC90, and CER1. Each is linked with EPS8L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPS8L1-to-partner and partner-to-EPS8L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by EPS8L1-low versus EPS8L1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L1→partner) and Y-score (partner→EPS8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C10orf53 →	+0.035	+4.867	<.001	.009	3	3
STOMACH	OC90 →	+0.022	+4.285	<.001	.007	3	2
URINARY_TRACT	CER1 →	+0.026	+5.087	<.001	.004	3	1
CNS	OOSP3 →	+0.049	+3.719	.003	.009	3	1
STOMACH	IL17A →	+0.030	+4.285	<.001	.007	3	1
STOMACH	OR8D4 →	+0.032	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

C10orf53 by EPS8L1 expression — BLOOD_Lymphoma

Explore this box plot interactively →