EPS15P1

Across TCGA pan-cancer cohorts, EPS15P1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated EPS15P1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher EPS15P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EPS15P1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and SKCM show a favorable association.

KIRP, KIRC, and BRCA are the cancer types where EPS15P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Quartile	All	0.489	0.788	<.001	105	view →
KIRC	OS	Median	All	0.550	0.697	<.001	87	view →
BRCA	DFS	Tertile	All	0.856	0.913	.002	69	view →
SARC	DFS	Tertile	All	0.471	0.659	<.001	40	view →
KICH	DFS	Median	All	0.539	1.000	<.001	31	view →
LIHC	OS	Tertile	All	0.479	0.701	.012	21	view →
GBM	DFS	Quartile	All	0.113	0.334	<.001	18	view →
ACC	OS	Tertile	All	0.523	0.920	.001	18	view →
PAAD	DFS	Tertile	All	0.252	0.437	.012	16	view →
COAD	DFS	Tertile	IV	0.250	0.524	.013	12	view →
LUAD	OS	Median	All	0.776	0.844	.014	12	view →
CHOL	OS	Tertile	All	0.122	0.668	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

EPS15P1–KIRP (OS)

Open the KIRP breakdown →