EPS15P1

Across TCGA pan-cancer cohorts, EPS15P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of EPS15P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where EPS15P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EPS15P1 is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.

LUAD, LUSC, and THCA are the cancer types where EPS15P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EPS15P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.325	<.001	9	view →
LUSC	All	All	+0.095	.002	3	view →
THCA	All	All	−0.019	.003	3	view →
BLCA	All	All	+0.351	.043	2	view →
STAD	Male	IV	−0.105	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

EPS15P1–LUAD

Open the LUAD breakdown →