EPS15L1

Across TCGA cell cohorts, EPS15L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,472 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EPS15L1-associated GO terms across cancer lineages are Regulation of glycolytic process through fructose-6-phosphate, Negative regulation of glycolytic process through fructose-6-phosphate, and Regulation of cell fate commitment. Each is linked with EPS15L1 in more than 13 cancer types. Because this analysis shows association rather than direction, both EPS15L1-to-partner and partner-to-EPS15L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glycolytic process through fructose-6-phosphate grouped by EPS15L1-low versus EPS15L1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS15L1→partner) and Y-score (partner→EPS15L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of glycolytic process through fructose-6-phosphate →	+0.114	+0.570	<.001	.002	3	14
LUNG_NSCLC_LUSC	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.114	+0.570	<.001	.002	3	14
SOFT_TISSUE	Regulation of cell fate commitment →	+0.109	+0.527	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of autophagosome maturation →	+0.112	+0.663	<.001	.004	3	13
OESOPHAGUS	Positive regulation of T-helper 17 cell lineage commitment →	+0.208	+0.653	.002	.001	3	13
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.119	+0.467	.003	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,472 associations by consensus.

Regulation of glycolytic process through fructose-6-phosphate by EPS15L1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →