EPS15

Across TCGA cell cohorts, EPS15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,615 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPS15-associated GO terms across cancer lineages are Postsynaptic neurotransmitter receptor internalization, Neurotransmitter receptor internalization, and Postsynaptic endocytosis. Each is linked with EPS15 in more than 14 cancer types. Because this analysis shows association rather than direction, both EPS15-to-partner and partner-to-EPS15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynaptic neurotransmitter receptor internalization grouped by EPS15-low versus EPS15-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS15→partner) and Y-score (partner→EPS15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Postsynaptic neurotransmitter receptor internalization →	+0.151	+0.884	.007	.001	3	15
STOMACH	Neurotransmitter receptor internalization →	+0.151	+0.884	.007	.001	3	15
STOMACH	Postsynaptic endocytosis →	+0.151	+0.884	.007	.001	3	15
BREAST	Positive regulation of receptor recycling →	+0.078	+0.405	<.001	.001	3	15
SKIN	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.061	+0.427	.001	.001	3	12
URINARY_TRACT	Monoubiquitinated protein deubiquitination →	+0.152	+1.118	.004	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,615 associations by consensus.

Postsynaptic neurotransmitter receptor internalization by EPS15 expression — STOMACH

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