EPPIN

Across TCGA cell cohorts, EPPIN RNA expression is significantly associated with the go_rna of many other GO terms, with 875 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible EPPIN-associated GO terms across cancer lineages are Negative regulation of flagellated sperm motility, Negative regulation of cilium-dependent cell motility, and Negative regulation of cilium movement. Each is linked with EPPIN in more than 11 cancer types. Because this analysis shows association rather than direction, both EPPIN-to-partner and partner-to-EPPIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of flagellated sperm motility grouped by EPPIN-low versus EPPIN-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPPIN→partner) and Y-score (partner→EPPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of flagellated sperm motility →	+0.231	+0.182	<.001	.005	3	12
BREAST	Negative regulation of cilium-dependent cell motility →	+0.231	+0.182	<.001	.005	3	12
BREAST	Negative regulation of cilium movement →	+0.231	+0.182	<.001	.005	3	12
UPPER_AERODIGESTIVE_TRACT	Response to unfolded protein →	+0.070	+0.076	<.001	.007	3	8
BREAST	Regulation of lung ciliated cell differentiation →	+1.580	+0.178	<.001	.006	3	8
BREAST	Positive regulation of lung ciliated cell differentiation →	+1.482	+0.178	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 875 associations by consensus.

Negative regulation of flagellated sperm motility by EPPIN expression — BREAST

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