EPPIN-WFDC6

Across TCGA pan-cancer cohorts, EPPIN-WFDC6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of EPPIN-WFDC6’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where EPPIN-WFDC6 RNA is repressed in tumor relative to normal tissue. In most cancer types EPPIN-WFDC6 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and THCA are the cancer types where EPPIN-WFDC6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EPPIN-WFDC6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	−0.292	<.001	7	view →
LUSC	All	II,III,IV	−0.246	<.001	6	view →
THCA	All	All	−0.074	<.001	6	view →
BRCA	Female	All	+0.050	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

EPPIN-WFDC6–LUAD

Open the LUAD breakdown →