Across TCGA patient cohorts, EPOR mutation is significantly associated with the RNA expression of many other genes, with 820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPOR-associated genes across cancer lineages are SETP7, MT1CP, and INSL4. Each is linked with EPOR in more than 1 cancer types. Because this analysis shows association rather than direction, both EPOR-to-partner and partner-to-EPOR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPOR→partner) and Y-score (partner→EPOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SETP7 →	+0.110	+3.423	<.001	.006	3	2
BLCA	MT1CP →	+0.226	+3.432	.003	.009	3	2
UCEC	INSL4 →	+0.570	+2.306	.004	.001	3	2
UCEC	RN7SKP286 →	+0.047	+4.060	<.001	.006	3	2
BRCA	TBC1D3H →	+0.058	+6.016	<.001	.002	3	1
UCEC	ZNF280B →	+0.539	+3.592	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 820 associations by consensus.

Exploration

EPOR survival (RNA) · tumor vs normal (RNA) · all EPOR data types