Across TCGA pan-cancer cohorts, EPOR RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated EPOR data layer compared with 6 for mutation status.
The strongest signal is observed in mesothelioma (MESO), where higher EPOR RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EPOR expression acts as an unfavorable survival marker, although some lineages such as BLCA and ACC show a favorable association.
MESO, KIRP, and BLCA are the cancer types where EPOR RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.