Across TCGA cell cohorts, EPOR mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EPOR-associated genes across cancer lineages are OR10H2, KRTAP19-8, and USP17L13. Each is linked with EPOR in more than 1 cancer types. Because this analysis shows association rather than direction, both EPOR-to-partner and partner-to-EPOR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPOR→partner) and Y-score (partner→EPOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR10H2 →	+0.038	+3.700	<.001	.005	3	1
OVARY	KRTAP19-8 →	+0.246	+4.222	<.001	.006	3	1
OVARY	USP17L13 →	+0.008	+4.222	<.001	.006	3	1
OVARY	USP17L17 →	+0.008	+4.222	<.001	.006	3	1
LARGE_INTESTINE	MAGEB4 →	+0.029	+5.415	<.001	.004	3	1
LARGE_INTESTINE	STRA8 →	+0.215	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

EPOR survival (RNA) · tumor vs normal (RNA) · all EPOR data types